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朱闻君

来源: 时间:2022-02-21 编辑:swzy2 点击:

个人简介模板


姓名:

朱闻君


办公地址:



联系电话:



电子邮箱:

zhuwenjun2002@163.com

简要描述

本实验室主要从事:(1)植物病害真菌灰葡萄孢(Botrytis cinerea)分泌蛋白的功能研究;(2)十字花科植物炭疽菌希金斯刺盘孢(Colletotrichum higginsianum)致病相关基因的功能研究;(3)植物与病原微生物互作的分子机理研究;(4)药食两用真菌茯苓(Wolfiporia cocos)的基因功能研究。


教育经历


2014/10 -2017/02Tel-Aviv UniversityDepartment of Molecular Biology and Ecology of Plants, Faculty of Life Science,博士后;

2006/09 -2012/12,华中农业大学,植物科技学院,植物病理,博士;

2002/09 -2006/06,华中师范大学,生命科学院,生物技术,本科学士。

工作经历


201410-20172月:以色列特拉维夫大学 (Tel-Aviv University),博士后,从事:1)植物病害真菌灰葡萄孢(Botrytis cinerea)致病相关分泌蛋白的筛选及其致病机理研究;(2)植物内生菌诱导植物抗逆机理的研究;

20201至今:武汉轻工大学,生命科学与技术学院,副教授;

201212201912武汉轻工大学,生命科学与技术学院,讲师。

研究方向:

1)植物病害真菌灰葡萄孢(Botrytis cinerea)分泌蛋白的功能研究;(2)十字花科植物炭疽菌希金斯刺盘孢(Colletotrichum higginsianum)致病相关基因的功能研究;(3)植物与病原微生物互作的分子机理研究;(4)药食两用真菌茯苓(Wolfiporia cocos)的基因功能研究。

主要承担的科研项目:


1主持国家自然科学基金面上项目:弱活性小分子分泌蛋白BC1G_01444在灰葡萄孢与植物互作过程中的功能机理研究(31972215),57万,2020.01-2023.12

2主持国家自然科学基金青年科学基金项目:致病相关分泌蛋白BC1G_08363BC1G_15201在灰葡萄孢致病过程中的作用及其机理研究(31501587),22.8万,2016.01-2018.12

3合作参与国家自然科学基金面上项目:甾醇氧乙酰基转移酶(SOAT)在茯苓酸生物合成途径中的功能解析(81872948),57, 2019.01-2022.12

4合作参与2018年度国家自然科学基金委员会与以色列科学基金会合作研究项目:利用真菌病毒研究葡萄孢和植物的相互作用(31861143043),160万,201911-20211231日。

5主持湖北省农业科学院植保土肥研究所开放基金课题:小分子分泌蛋白BC1G_01016在灰葡萄孢与植物互作过程中的功能机理研究(2018ZTSJJ14),4万,201810-20209月。

6主持横向项目:中药材及其致病菌组学相关研究(whpu-2018-cg-138),5万,201911-20201231日。

代表性论文与著作


通讯作者(*)或第一作者:

  1. Zhu W*, Yu M, Xu R, Bi K, Yu S, Xiong C, Liu Z, Sharon A, Jiang D, Wu M, Gu Q, Gong L, Chen W, Wei W*. (2022). Botrytis cinerea BcSSP2 protein is a late infection phase, cytotoxic effector. Environmental Microbiology. https://doi.org/10.1111/1462-2920.15919

  2. Zhu W, Liu Y, Tang J, Liu H, Jing N, Li F, Xu R*, Shu S*. (2022). Functional analysis of sterol O-acyltransferase involved in the biosynthetic pathway of pachymic acid in Wolfiporia cocos. Molecules. 27: 143.

  3. 周鹏,朱闻君*. (2020). 湖北枣阳烟区烟叶赤星病病原鉴定. 安徽农业科学,J. Anhui Agric. Sci. 48(3): 146-148, 192.

  4. Zhu W, Xu X, Peng F, Yan D, Zhang S, Xu R, Wu J, Li X, Wei W*, Chen W*. (2019). The cyclase-associated protein ChCAP is important for regulation of hyphal growth, appressorial development, penetration, pathogenicity, conidiation, intracellular cAMP level, and stress tolerance in Colletotrichum higginsianum. Plant Science. 283: 1–10.

  5. Zhu W*, Wei W, Zhang S, Zheng Y, Chen P, Xu X. (2018). The phosphatome of medicinal and edible fungus Wolfiporia cocos. Current Microbiology. 75: 124–131.

  6. Zhu W, Ronen M, Gur Y, Minz-Dub A, Masrati G, Ben-Tal N, Sharon I, Savidor A, Eizner E, Valerius O, Braus G, Bowler K, Bar-Peled M, Sharon A*. (2017). BcXYG1, a secreted xyloglucanase from Botrytis cinerea, triggers both cell death and plant immune responses. Plant Physiology. 175: 438-456.

  7. Zhu W*, Wei W, Wu Y, Zhou Y, Peng F, Zhang S, Chen P, Xu X. (2017). BcCFEM1, a CFEM domain-containing protein with putative GPI-anchored site, is involved in pathogenicity, conidial production and stress tolerance in Botrytis cinerea. Frontiers in Microbiology. 8: 1807.

  8. Zhu W*, Zhou M, Xiong Z, Peng F, Wei W*. (2017). The cAMP-PKA signaling pathway regulates pathogenicity, hyphal growth, appressorial formation, conidiation, and stress tolerance in Colletotrichum higginsianum. Frontiers in Microbiology. 8: 1416.

  9. Wei W, Shu S, Zhu W*, Xiong Y, Peng F. (2016). The kinome of edible and medicinal fungus Wolfiporia cocos. Frontiers in Microbiology. 7: 1495.

  10. Wei W, Xiong Y, Zhu W*, Wang N, Yang G, Peng F. (2016). Colletotrichum higginsianum mitogen-activated protein kinase ChMK1: role in growth, cell wall integrity, colony melanization and pathogenicity. Frontiers in Microbiology. 7: 1212.

  11. Zhang S, Hu B, Wei W, Xiong Y, Zhu W*, Peng F, Yu Y, Zheng Y, Chen P*. (2016). De novo analysis of Wolfiporia cocos transcriptome to reveal the differentially expressed carbohydrate-active enzymes (CAZymes) genes during the early stage of sclerotial growth. Frontiers in Microbiology. 7: 83.

  12. Wu Y, Zhu W (Co-first author), Wei W, Zhao X, Wang Q, Zeng W, Zheng Y, Chen P*, Zhang S*. (2016). De novo assembly and transcriptome analysis of sclerotial development in Wolfiporia cocos. Gene. 588: 149-155.

  13. Sun Q, Wei W, Zhu W*, Zhang S, Song J, Zheng Y, Chen P*. (2015). Genetic diversity of Chinese Wolfiporia cocos cultivars revealed by phenotypic traits and ISSR markers. Mycological Progress. 14: 61.

  14. Sun Q, Wei W, Zhao J, Song J, Peng F, Zhang S, Zheng Y, Chen P, Zhu W*. (2015). An efficient PEG/CaCl2-mediated transformation approach for the medicinal fungus Wolfiporia cocos. Journal of Microbiology and Biotechnology. 25: 1528-1531.

  15. Zhu W, Wei W, Fu Y, Cheng J, Xie J, Li G, Yi X, Kang Z, Dickman MB, Jiang D*. (2013). A secretory protein of necrotrophic fungus Sclerotinia sclerotiorum that suppresses host resistance. PLoS ONE. 8: e53901.

非通讯作者或非第一作者:

  1. Bi K, Scalschi L, Jaiswal N, Mengiste T, Fried R, Sanz AB, Arroyo J, Zhu W, Masrati G, Sharon A* (2021) The Botrytis cinerea Crh1 transglycosylase is a cytoplasmic effector triggering plant cell death and defense response. Nat Commun. 12: 2166.

  2. Doehlemann G*, Ökmen B, Zhu W, Sharon A (2017) Plant pathogenic fungi. Microbiol Spectrum 5(1): FUNK-0023-2016. doi: 10.1128/microbiolspec.FUNK-0023-2016.

  3. Liu X, Wei W*, Zhu W, Su L, Xiong Z, Zhou M, Zheng Y, Zhou D-X* (2017) Histone deacetylase AtSRT1 regulates metabolic flux and stress response in Arabidopsis. Mol Plant. 10: 1510-1522.

  4. Yu Y*, Xiao J, Zhu W, Yang Y, Mei J, Bi C, Qian W, Qing L, Tan W (2017) Ss-Rhs1, a secretory Rhs repeat-containing protein, is required for the virulence of Sclerotinia sclerotiorum. Mol Plant Pathol 18: 1052-1061.

  5. Eizner E, Ronen M, Gur Y, Gavish A, Zhu W, Sharon A* (2017) Characterization of Botrytis-plant interactions using PathTrack© - an automated system for dynamic analysis of disease development. Mol Plant Pathol 18: 503-512.

  6. Wei W, Zhu W, Cheng J, Xie J, Jiang D, Li G, Chen W, Fu Y* (2016) Nox complex signal and MAPK cascade pathway are cross-linked and essential for pathogenicity and conidiation of mycoparasite Coniothyrium minitans. Sci Rep 6: 24325.

  7. Shlezinger N, Israeli M, Mochly E, Oren-Young L, Zhu W, Sharon A* (2016) Translocation from nuclei to cytoplasm is necessary for anti A-PCD activity and turnover of the Type II IAP BcBir1. Mol Microbiol 99: 393-406.

  8. Zhang S, Wang R, Zeng W, Zhu W, Zhang X, Wu C, Song J, Zheng Y, Chen P* (2015) Resource investigation of traditional medicinal plant Panax japonicus (T.Nees) C.A. Mey and its varieties in China. J Ethnopharmacol 166: 79-85.

  9. Zhang S, Wu Y, Jin J, Hu B, Zeng W, Zhu W, Zheng Y*, Chen P* (2015) De novo characterization of Panax japonicus C. A. Mey transcriptome and genes related to triterpenoi saponin biosynthesis. Biochem Bioph Res Co 466: 450-455.

Wei W, Zhu W, Cheng J, Xie J, Li B, Jiang D, Li G, Yi X, Fu Y* (2013) CmPEX6, a gene involved in peroxisome biogenesis, is essential for parasitism and conidiation by sclerotial parasite Coniothyrium minitans. Appl Environ Microb 79: 3658-3666.

专利成果:


获奖:


(1)   Post-Doctoral Program for outstanding Post-Doctoral Researchers from China   & India 2016-2017;

(2)   Post-Doctoral Program for outstanding Post-Doctoral Researchers from China   & India 2015-2016;

(3)   Post-Doctoral Program for outstanding Post-Doctoral Researchers from China   & India 2014-2015

其它: